Sibutramine

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$35.00
Quanity:
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Characteristics

ACTIVE HALF-LIFE
1 hour
Classification
Non-steroidal anorexiant
Dosage
10-15 mg/day
ACNE
No
WATER RETENTION
No
HBR
Perhaps
HEPATOTOXICITY
Low
AROMATIZATION
No
Active Substance
FORM
54 pills x 15 mg
Manufacturer

Shipping Information

  • Currently, orders from our International Premium Warehouse 1 can be shipped to continental United States only .
  • Temporary shipping restrictions apply to Hawaii and Alaska.
  • Military addresses (including APO, FPO, etc.) are currently not supported.
  • PO Box deliveries are available exclusively through our domestic warehouse (USA Warehouse 1).

Description

Sibutramine is a non-steroidal anorexigenic drug that enhances the feeling of satiety. The drug is a direct serotonin and norepinephrine reuptake inhibitor, structurally similar to amphetamine. It belongs to a group of drugs for the treatment of obesity and is used in a comprehensive maintenance treatment of patients with overweight.  Sibutramine hydrochloride appeared on the market in 1998 under the brand name Meridia from the Abbot Laboratories Company.

Sibutramine acts in two ways: 

  • Inhibits the reuptake of neurotransmitters serotonin and norepinephrine from synoptic gap, which reduces appetite and food intake (increases the feeling of satiety). In studies subjected patients reduced the daily ration by 1,300 calories.
  • Stimulates metabolism and increases thermogenesis. This fat burning effect occurs due to the indirect impact on beta-3-adrenoreceptors, which are responsible for fat burning. 

Sibutramine converts by the liver into metabolites that significantly surpass sibutramine itself  in the ability to inhibit serotonin and norepinephrine reuptake.

Customer Reviews


02.04.2019
Nattan
Rating: BAD
Verified Purchase
I started to take 20mg this morning and didnt help to decrease my appetite. I wonder if this product is legit. This sibutramine doesnโ€™t work at all. Iโ€™m very disappointed!
26.03.2019
sibutramine
Rating: BAD
Verified Purchase
I'm taking 20mg. per day I saw no change in my appetite, my heart rate did not change, so I wonder if this its really help to Stimulates metabolism and increases thermogenesis.
very disappointed
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